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Close the Calcium Gap

Maintaining proper calcium status in your dairy cows is critical during the transition period to help minimize the occurrence and impact of hypocalcemia and other costly consequences of low blood calcium. Vitamin D3 plays a critical role in maintaining normal blood calcium concentrations by helping to increase the absorption of dietary calcium. Hy•D® is a unique form of vitamin D3 that has been demonstrated to positively affect blood calcium concentrations beyond other forms of vitamin D3.

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Studies Support the Benefits of Feeding Hy•D

11percent

Average Increase in Energy Corrected Milk1-4

throughday

Increase Postpartum Blood Calcium Concentrations3

28percent

Average Increase in Colostrum Yield1-3

1 Martinez et. al., 2018. J. Dairy Sci. 101:2544.
2 Silva et. al., 2022. J. Dairy Sci. 105:5796.
3 Poindexter et. al., 2023. J. Dairy Sci. 106:974.
4 Holub et al., 2023. ASAS Annual Meeting. Abstract #508084.
*Results may vary

Hy•D Puts Calcium on the Fast Track

Feeding Hy•D increases the available pool of calcidiol (25(OH)D3), leading to a better vitamin D3 status and more efficient absorption of calcium.

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1. The Liver

When vitamin D3 is fed, it must first be absorbed and then presented to the liver to be converted to 25(OH)D3.

2. Hy•D Bypasses the Liver

When Hy•D is fed, it bypasses the animal’s liver to ensure the direct availability of calcidiol. The liver can act like a bottleneck and inhibit the conversion of D3 to 25(OH)D3, particularly during periods of high metabolic activity, such as the transition period.

3. The Kidney

When required, as in times of low blood calcium status, the kidney converts 25(OH)D3 into the active form of vitamin D3, called 1,25-dihydroxyvitamin D3. One of the primary modes of action of 1,25- dihydroxyvitamin D3 in the transition cow is to increase the absorption of dietary calcium to help maintain normal blood calcium concentrations.

4. A More Optimal Vitamin D Status

Research has demonstrated that higher blood concentrations of calcidiol 25(OH)D3 during the transition period help support calcium homeostasis,1 increase some aspects of immune cell function,2 increase milk yield1,3 and tend to improve reproductive performance.2

1Phibro Animal Health 2020. | 2Martinez et al., 2018. J. Dairy Sci. 101:2544. | 3Martinez et al., 2018. J. Dairy Sci. 101:2563.

Hy•D helps support calcium homeostasis through a unique source of vitamin D3 called calcidiol (25(OH)D3).

Studies have demonstrated that the addition of 3 mg of calcidiol along with a basal level
of vitamin D3 from cholecalciferol (minimum of 20,000 IU) can lead to significant herd
health and production advantages.

  • Feeding calcidiol along with cholecalciferol works better than supplementing
    with cholecalciferol alone.
  • Unique mode of action eliminates the need for conversion in the liver and
    allows for faster, more consistent absorption.

Dairy Herd Health Resources

Informative research trials and helpful resources to support dairy herd health.

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How to Incorporate Dietary Vitamin D3 into an Animate® Program for Prepartum Dairy Cows

Report
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The Role of Vitamin D3 in Regulation of Calcium Homeostasis in Dairy Cattle Metabolism

Report

You Herd Right Podcast

You Herd Right Podcast

Take a deep dive into a range of topics, tactics and innovations in dairy production. Gain greater insights into dairy cow health and the success of dairy operations. Hear from experts in the field as we dig into the details and best practices for nutrition, animal health and dairy cattle management.

    Episodes include:

  • Research supports fully acidogenic, high dietary calcium diets.
  • Feeding and managing your prepartum dairy cows.
  • Mineral guidelines.
  • Compensated metabolic acidosis.

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Frequently Asked Questions

What is Hy•D?
Hy•D, a vitamin D3 metabolite called calcidiol (25(OH)D3), fast-tracks the transition phase to help give dairy cows better performance.
What does Hy•D do?
Hy•D improves calcium management and productivity of dairy cows and works better than supplementing with vitamin D3 alone.
Why is managing calcium important?
Maintaining proper calcium status in your dairy cows is critical during the transition period to prevent hypocalcemia and other costly consequences of low blood calcium.
Why use Hy•D to manage calcium?
Hy•D helps support calcium homeostasis through a unique source of vitamin D3 called calcidiol (25(OH)D3). Studies have demonstrated that the addition of 3 mg of calcidiol along with a basal level of vitamin D3 from cholecalciferol (minimum of 20,000 IU) can lead to significant herd health and production advantages.

The unique mode of action of Hy•D eliminates the need for conversion in the liver, thus directly providing the main circulating form of vitamin D. Including Hy•D in a total mixed ration (TMR) allows for faster, more consistent absorption helping to close the calcium gap.

Talk to your dairy advisor

Learn how feeding Hy•D can help support herd health and productivity.