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Numerous scientific trials and large-scale commercial use have demonstrated that Magni-Phi, a proprietary blend of polyphenols including quillaja and yucca, can help modulate the immune system of poultry. A balanced immune system can help alleviate inflammatory tissue damage related to live coccidiosis vaccination and, at the same time, help support the immunity development against coccidiosis. This may lead to higher body weight gain and lower feed conversion and mortality of coccidiosis vaccinated birds.

Quillaja and yucca polyphenols in Magni-Phi can help improve the immune response of poultry. An improved immune response can help alleviate non-specific inflammation and may improve leaky gut syndrome. Quillaja saponins can also help stimulate a specific, mostly cell-mediated, immune response to different pathogens, including bacteria, viruses or protozoa. Improved immune response can help improve intestinal morphometrics, absorption of nutrients, body weight gain and feed conversion ratio and may help reduce pathogen load.

Probiotics are live microorganisms that, when provided in adequate amounts, can colonize the intestinal tract and produce metabolites. These metabolites can provide benefits to the host. Probiotics need specific conditions and nutrient substrates to affect the intestinal microbiome and produce the respective metabolites. Magni-Phi nutritional specialty product is a phytogenic product containing quillaja and yucca saponins and polyphenols that help to modulate the host’s immune system. A well-balanced immune system can help reduce inflammation and stimulate a specific immune response to different pathogens.

We have not observed in research any harmful effects of Magni-Phi on good bacteria in the gut. We continue to run microbiota analysis in an applied research setting to learn more.

The effect of Magni-Phi has been evaluated in research trials on three different types of coccidiosis vaccines: those containing attenuated, virulent, or a mixture of attenuated and virulent coccidia. Despite lower oocyst counts during that initial period, immunity offered by the vaccines was not compromised. In one study, following a severe challenge at day 28, coccidia lesion scores were not significantly different between vaccinated birds fed diets either with or without Magni-Phi. Vaccinated birds fed Magni-Phi had significantly improved feed conversions at both 28 and 42 days of age. The complete trial was published in Poultry Science and details can be found at: https://pubmed.ncbi.nlm.nih.gov/33518338/.

The average saponin concentration in Magni-Phi, is approximately 4.4% w/w.

The first choice is to use Magni-Phi from start to finish. The next best choice is to use it early (starter and grower feed rations).

You can use 250, 375 or 500 ppm. The effects on the product are feeding level dependent.

No, we have research that shows that Magni-Phi modulates the cycling between 30% and 60% based on the species of coccidian. Cycling time is not affected. We have also shown that immunity provided by the vaccine is not affected. In these same trials, we’ve seen performance parameters of the birds fed Magni-Phi improve over control birds.

Magni-Phi has been used to support and help improve gut health which leads to better pathogen control and nutrient absorption. This results in improved productivity in antibiotic-free / no antibiotics ever / organic systems. As we have more producers adopt the use of Magni-Phi, we are learning more and more about the effects on the intestinal tract from the digestibility standpoint. These effects can lead to better performance and yield but may also help decrease the colonization of other relevant pathogens that plague the chicken production system. Producers also use Magni-Phi in their broiler and breeder coccidiosis vaccine programs as it modulates the deleterious effect of the coccidia vaccine on the intestinal tract. The delivery systems for these vaccines are less than ideal and on occasion leave some birds without exposure to the parasite. In addition, the management program of the birds during rearing plays a crucial role in the cycling of the parasite, which leads to immunity. The use of Magni-Phi helps the producer avoid the possible mistakes produced during the events that can lead to serious breaks of coccidiosis or even necrotic enteritis. Magni-Phi can also be used in combination with ionophores, essential oils, chemical anticoccidials and coccidiosis vaccines – after over 50 controlled studies we have confirmed with confidence that Magni-Phi has an additive effect on the performance of these technologies.

In numerous field applications and over 50 controlled trials, birds fed Magni-Phi have shown improved intestinal health and increased villus structure, leading to improved nutrient digestibility and better bird performance. Absorption of fats, minerals and proteins increases as a result of feeding Magni-Phi. This increased nutrient absorption results in better body weights. Improved growth is highly correlated with better carcass yield. Studies show that when birds were fed Magni-Phi whole carcass yield was improved 1.6% and feed conversion improved by five points¹. Feeding Magni-Phi improves growth performance and efficiency of feed utilization because the intestine is healthier. ^{1K. W. Bafundo, K. Männer & I. Duerr (2021): The combination of quillaja and yucca saponins in broilers: effects on performance, nutrient digestibility and ileal morphometrics, British Poultry Science, DOI:10.1080/00071668.2021.1891523}

Both compounds that make up Magni-Phi have a specific action on the immune response of poultry. The Quillaja saponin works to stimulate the immune system which helps prevent pathogen attachment to the host and the Yucca saponin modulates the host’s innate and adaptive immune systems. In simple terms, it improves the digestive system of poultry to help fight off the pathogens and leaves those cells to work on absorption of nutrients, which translates into an improved digestibility of protein, fats and minerals.

Magni-Phi nutritional specialty product contains a specialized proprietary blend of triterpenoid and steroidal saponins from Quillaja saponaria from Chile and Yucca schidigera. It is a natural solution that promotes the intestinal integrity of poultry, which helps improve defense against pathogens. It fits in today’s poultry production environment since it meets the need to produce antibiotic-free protein.